Formalin-fixed, paraffin-embedded (FFPE) tissue sections are valuable sample sources for biomedical research. FFPE technique preserves the morphology and cellular details of the tissues for long periods. This technique also allows storage of tissue samples at ambient temperatures, which translates to convenience and cost-effectiveness. FFPE tissues likely represent the most common source of archived biological material…. Read article →
Recently, we gave a series of webinars covering the different challenges and possible solutions for getting reliable gene expression profiles, with a focus on RNA extraction and stabilization from challenging samples. During these webinars, the audience had a variety of interesting questions. We would like to share with you our answers to the top 9… Read article →
In today’s clinical and translational research, blood is one of most common biospecimens being used. Although the highest DNA yield and quality is achieved by purifying genomic DNA from freshly harvested material, regretfully most of our precious samples cannot be processed straight away. That´s why sample management is so crucial right from the very start…. Read article →
Browse through PubMed and perform a search with keywords like transcriptomics, proteomics, genomics, sequencing or amplification. Pick any paper answering questions in cancer research, neurobiology, stem cell biology, immunology or developmental biology. Are you amazed by how often you come across the term “single-cell”? Don’t be! The field of single-cell analysis has grown enormously in the recent years. Nature… Read article →
There’s a growing trend of irreproducible results in biomedical research. In a previous post, Kurchi Bhattacharya reported on recent studies finding that a surprising number of scientists could not only not reproduce the results of their colleagues, but many found their own results difficult to reproduce as well. Much of the reproducibility problem likely has… Read article →
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