Genomic DNA (gDNA) is chromosomal DNA that holds the complete set of genetic data for an organism – unlike plasmids, were the DNA is extrachromosomal. Sizes and molecular weights of various gDNAs can vary from organism to organism. The highest DNA yield and quality is achieved by purifying gDNA from freshly harvested tissues and cells…. Read article →
Researchers who wish to perform large-scale studies that integrate sample data across multiple biobanks face many challenges. Biobanks are often separated by country and by institution – creating independent, unlinked collections of information. Every biobank has its own procedures for collecting sample data, storing information, processing samples and storing samples. Regulatory procedures designed to protect… Read article →
Recently, I had the opportunity to meet with Dr. Fay Betsou at the Integrated BioBank of Luxembourg (IBBL) Institute and conduct an interview to understand more about the importance of biospecimen research, IBBL’s role and future trends. Biospecimen research is a key component of our approach to guaranteeing the quality of samples: first protocols are… Read article →
RNA is one of the most important samples in molecular biology. In your lab’s personal biobank, you might extract RNA from any number of sample types, from frozen cells to FFPE tissue, and the insights you can gain from analyzing it are crucial. Messenger RNA links genes to proteins, and transcriptome profiling can reveal much about the workings… Read article →
Research studies require high-quality samples in sufficient number to produce statistically significant results. Although biobanks have been collecting samples for decades, recent trends have emphasized large-scale projects, extensive clinical information associated with samples, and an emphasis on whole-genome analysis techniques (1). Biobanks are now significant players in clinical research studies, and international compatibility is a… Read article →
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