Biorepositories: implications of international collaborations

Research studies require high-quality samples in sufficient number to produce statistically significant results.  Although biobanks have been collecting samples for decades, recent trends have emphasized large-scale projects, extensive clinical information associated with samples, and an emphasis on whole-genome analysis techniques (1). Biobanks are now significant players in clinical research studies, and international compatibility is a… Read article →


Sharing, integrating and standardizing data: 3 biobanking informatics trends to watch in 2016

Three New Year’s resolutions for many biobanks in 2016 might just reflect the 3 emerging biobanking informatics trends highlighted this year by the International Society for Biological and Environmental Repositories (ISBER) Informatics Working Group (1): 1. Sharing data 2. Integrating data 3. Standardizing data These trends will gain more attention as it becomes increasingly important… Read article →


Biobanking: the impact of low-concentration storage on RNA integrity

Biobanks frequently freeze samples to store them for future research use, but maintaining quality of nucleic acids under frozen conditions can be tricky. Following specific quality practices can ensure the preservation of RNA, which is crucial for maintaining samples for clinical studies. Storage conditions, including the temperature and the length of time tissues and purified RNA stay… Read article →


Cryopreservation of human mesenchymal stem cells for clinical applications

Mesenchymal stem cells (MSCs) are anchorage-dependent, non-hematopoietic fibroblast-like stem cells with multi‑lineage potential. They can be induced to differentiate into many cell types, including osteoblasts, myoblasts, adipocytes and chondrocytes. Although they were originally detected in bone marrow, they have also been found in dental pulp, adipose tissue and amniotic fluid. More than 500 clinical trials… Read article →