General

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Let’s celebrate DNA Day!

April 25, 1953, is a day to remember. That’s the day, sixty-five years ago, that DNA’s double-helical structure was published for the first time in a paper by James Watson and Francis Crick. The paper, printed in the journal Nature, together with papers from Maurice Wilkins and Rosalind Franklin, included evidence that the structure existed… Read article →


curling

Smoothing the path to successful RNA isolation

I’m always excited to watch curling during the Winter Olympics – great teams from around the world competing and aiming for nothing less than gold. It might look easy as they try to get the stone as close to the button as possible. But it is really much more difficult, because there are so many… Read article →




QIAGEN QIAseq SPE Chemistry

QIAseq and Single Primer Extension Chemistry: Redefining Amplicon-Based NGS

Targeted NGS has been widely used for the detection and confirmation of genetic changes, yet there are technical challenges that undermine precise quantification and confound analyses. Multiplex PCR and nested PCR-based library preparation approaches present primer design and specificity challenges inherent to these methods. Amplicon-based next-generation sequencing (NGS) assays offer many advantages for targeted enrichment…. Read article →