Liquid Biopsy




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Breaking the metastasis cycle: Is ROS-activated β-globin expression required for CTC survival?

Reactive oxygen species (ROS) are chemical molecules containing a highly reactive oxygen molecule. These molecules are formed as by-products of cellular metabolism, but also serve intracellularly as signaling molecules. ROS examples include peroxides, superoxide, hydroxyl radical and singlet oxygen. When present within cells in significant amounts, ROS can be indicators of oxidative cellular stress, and… Read article →


Exosomes digestive tract

MicroRNA sorting in exosomes and determination of cell fate

Liquid biopsy, that is, sampling and analysis of DNA, RNA and proteins found in blood or other body fluids, offers a potentially non-invasive and cost-effective way to gain insight into cancer and other disease detection and progression. Within blood, both healthy and diseased cells release small vesicles termed extracellular vesicles (EVs) that carry information from… Read article →