Circulating Tumor Cells


Sampling of CTCs reveals drug-resistance mechanisms in prostate cancer

CTC clusters: biological significance and label-independent isolation using microchip technology Clusters of CTCs, consisting of two or more cells, have been observed for decades. Their significance is unknown, but a recent study suggests that a cluster is approximately 50 times more likely to result in a metastatic event compared to a single CTC (1). In… Read article →


Circulating tumor cell (CTC) biomarkers in liquid biopsy – not ready for prime time?

Currently, the only FDA-approved use of circulating tumor cells (CTCs) is identifying and counting CTCs in whole blood from patients with metastatic breast, colon or prostate cancer (1). Based upon recent developments, enumeration of CTCs is only the tip of the iceberg. Molecular characterization of CTCs would permit noninvasive genotyping in real time, potentially sampling… Read article →


Getting insight into the body: it’s all about the blood

Blood tells us lots of things. From cardiovascular health to cholesterol to inflammation to vitamin D levels – there is no shortage of information. Historically, blood was used to determine physiological and biochemical states, such as disease and organ function – but now, there are new technologies being developed to run the next generation of… Read article →