Non-coding RNA

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ncRNAs as circulating cancer biomarkers for liquid biopsy

Cancer biomarkers are critical at multiple points during the disease process. Novel biomarkers for cancer screening, obtained via liquid biopsies, would be of particular clinical value given the difficulty of early detection for lethal malignancies such as ovarian and pancreatic cancer. Even cancers that are easily detected could benefit from improved screening and staging methods…. Read article →


microRNA and lncRNA in lung cancer

miRNA and lncRNA – serum biomarkers for lung cancer

One of the most exciting potential applications of circulating non-coding RNAs like microRNA (miRNA) and long non-coding RNA (lncRNA) is as biomarkers for early detection of cancer. Cancer treatment, like treatment of many other diseases, can be far more effective when started early. Easily accessible markers like RNAs in the blood are an attractive possibility for finding… Read article →


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Profiling microRNA from exosomes and blood

Exosomes are nano-sized vesicles, secreted by all types of cells and found abundantly in biofluids like blood, saliva and urine. These extracellular vesicles carry multiple functional passengers including DNA, miRNA, non-coding RNA and proteins, and function as intercellular communication vehicles by transporting molecules between specific cells. microRNAs are small non-coding RNAs that play an intricate… Read article →