Liquid Biopsy

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Liquid biopsy: a necessity in the age of personalized medicine

The 2001 introduction of Imatinib (Gleevec) for the treatment of chronic myelogenous leukemia was a watershed moment in cancer therapeutics. In addition to treating a previously fatal leukemia, it opened the door for the further development of targeted therapeutics, molecules designed to specifically inhibit individual oncogenic proteins. The advent of targeted therapy also made the… Read article →




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ncRNAs as circulating cancer biomarkers for liquid biopsy

Cancer biomarkers are critical at multiple points during the disease process. Novel biomarkers for cancer screening, obtained via liquid biopsies, would be of particular clinical value given the difficulty of early detection for lethal malignancies such as ovarian and pancreatic cancer. Even cancers that are easily detected could benefit from improved screening and staging methods…. Read article →


microRNA and lncRNA in lung cancer

miRNA and lncRNA – serum biomarkers for lung cancer

One of the most exciting potential applications of circulating non-coding RNAs like microRNA (miRNA) and long non-coding RNA (lncRNA) is as biomarkers for early detection of cancer. Cancer treatment, like treatment of many other diseases, can be far more effective when started early. Easily accessible markers like RNAs in the blood are an attractive possibility for finding… Read article →