Liquid Biopsy

next-generation sequencing

From sample to insight: NGS for liquid biopsy and beyond

The use of high-throughput next-generation sequencing (NGS) technologies continues to provide a wealth of sequence data, resulting in significant advances in a wide range of research areas and applications. Key among these is liquid biopsy – the ability to sequence nucleic acids found in circulation will enable scientists to identify key mutations and more specifically distinguish… Read article →


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Circulating Biomarkers World Congress 2015

In March, the second annual SELECTBIO Circulating Biomarkers World Congress 2015 brought together academic researchers and industry participants to present research, industry and commercial activities in the translation of circulating biomarkers. Speakers presented unpublished data on extracellular vesicles and extracellular nucleic acids as circulating biomarkers, fitting into three overarching themes: • Circulating DNA, RNA and… Read article →


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Profiling microRNA from exosomes and blood

Exosomes are nano-sized vesicles, secreted by all types of cells and found abundantly in biofluids like blood, saliva and urine. These extracellular vesicles carry multiple functional passengers including DNA, miRNA, non-coding RNA and proteins, and function as intercellular communication vehicles by transporting molecules between specific cells. microRNAs are small non-coding RNAs that play an intricate… Read article →


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Getting insight into the body: it’s all about the blood

Blood tells us lots of things. From cardiovascular health to cholesterol to inflammation to vitamin D levels – there is no shortage of information. Historically, blood was used to determine physiological and biochemical states, such as disease and organ function – but now, there are new technologies being developed to run the next generation of… Read article →


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Revealing the hidden secrets in exosomes

Exosomes are small membrane vesicles or microvesicles, shed by cells into the bloodstream. They were considered as biological trash cans with the function of discarding or cleaning unwanted cellular particles, but scientists have discovered that they play an integral role in intercellular communication. Each exosome transmits DNA and RNA molecules through the blood and other… Read article →