Microbiome/Microbiology


Norovirus

Whole-genome sequencing as a tool in the diagnosis and characterization of norovirus

If you’ve never had norovirus, consider yourself one of the few and fortunate. Norovirus is the most common cause of acute gastroenteritis among adults and children in the United States with symptoms including fever, vomiting and diarrhea. It causes 19–21 million illnesses and contributes to 56,000–71,000 hospitalizations and 570–800 deaths yearly (1). The virus is… Read article →



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Combating antibiotic-resistant bacteria

The CDC estimates that each year in the United States, antibiotic-resistant bacteria sicken two million people, and at least 23,000 people die as a direct result. In addition, antibiotic resistance is a threat to animals, agriculture, and the economy. In March of 2015, the White House released a comprehensive national action plan to combat antibiotic-resistant… Read article →


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If you can’t grow it, you can’t study it. How can we sequence unculturable bacteria?

Sequencing bacteria helps us detect mutations that might be important for antibiotic resistance, virulence changes and other variations within a species. A major complication, though, is the fact that not every bacterium can be successfully grown in culture. So how can you sequence something when you can’t culture it? A recent study points to the… Read article →