Microbiome/Microbiology

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Metagenomics and microbial single cell genomics – a winning team

Deciphering the world around us – the “microbial dark matter” (1) – is a remaining challenge in environmental microbiology. Even after decades of 16S rRNA gene-based surveys, there are strong indications that the diversity of bacteria is still not exhaustively described even on high taxonomic (phylum) levels and that 16S rRNA sequences, representing novel bacterial… Read article →



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March webinar series: Explore the host response and defense mechanisms

The immune system is an intricate host defense system of unique, yet highly coordinated responses to pathogens. The immune response is divided into two phases – innate and adaptive. Innate immunity provides the first line of defense through different families of pattern-recognition receptors (PRRs), such as Toll-like receptors (TLRs). Adaptive immunity, in the form of… Read article →



Norovirus

Whole-genome sequencing as a tool in the diagnosis and characterization of norovirus

If you’ve never had norovirus, consider yourself one of the few and fortunate. Norovirus is the most common cause of acute gastroenteritis among adults and children in the United States with symptoms including fever, vomiting and diarrhea. It causes 19–21 million illnesses and contributes to 56,000–71,000 hospitalizations and 570–800 deaths yearly (1). The virus is… Read article →