The mammalian immune system is a complex, lethal collection of cells and molecules that controls and eliminates threats to the body. The innate branch launches a quick response from phagocytes and natural killer cells, while the adaptive branch generates memory cells to create long-lasting defense against a second exposure. However, the immune system isn’t foolproof…. Read article →
Accuracy, reliable controls and reproducibility. These are the foundations on which a healthy scientific literature is based. When we read papers, we check the methods section to see how the authors controlled for certain variables, whether the technologies used were appropriate for the question, and how many times the experiments were replicated. Everyone wants to find the… Read article →
Type I diabetes, formerly known as juvenile diabetes, is an insulin deficiency that mostly arises in childhood or young adulthood. In contrast to Type II diabetes, which results from insulin resistance, Type I diabetes is an autoimmune condition in which the immune system destroys the pancreatic cells that make insulin, the beta cells. The diagram below… Read article →
The field of microRNA research is in a period of inflection. While RNAi and microRNA have been growing in prominence since discoveries by Dr. Craig Melo and Dr. Andy Fire looking at the relationship of small, non-coding RNA with gene expression, there has been a growing sense of the importance of detecting and correlating microRNA… Read article →
For patients with solid tumors, metastatic disease often represents a turning point in their journey. It remains the most significant hurdle in cancer treatment, accounting for 90% of all deaths resulting from solid tumors (1). Research during the past 20 years has begun to elucidate multiple events that take place during metastatic progression. In the… Read article →
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