microRNA Biomarkers

LungCancer+miRNA_700x233

What is the future of microRNA technology?

Technology for profiling of microRNA by qPCR is ever evolving, opening up the opportunity for deeper insights into gene regulation. The development of locked nucleic acids (LNA), for example, enhanced qPCR primer specificity, while the design for an effective reverse transcription method for plant microRNAs opened up a new phylogenetic kingdom for qPCR profiling. Developing assays to… Read article →


Biogenesis

Back to the beginning: microRNA biogenesis

Introduction Since the discovery of microRNA (miRNA) in the early 1990s, much effort has been devoted to understanding how miRNAs are produced in the cell and how genes are controlled by these tiny RNAs. In today’s blog, we look back to the very beginning of miRNA discovery, and discuss miRNA biogenesis and its influence in cancer… Read article →


WEBINAR_700x233

The Bioscientist Webinar Festival – a pool of educational content

Here at QIAGEN, one of our main aims is to provide you with excellent, actionable resources that will support you in your research and experiments. As a result, we create content on a regular basis that can help you gain insights into important topics of scientific and specialized interest. As part of this ongoing effort,… Read article →


LungCancer+miRNA_700x233

Newly discovered biomarker miR-591 inhibits cancer cell proliferation and invasion

About 5000 years ago, the inhabitants in east Finland first discovered asbestos and used it to make their cooking utensils strong (1). In the mid-19th Century, the large-scale industrial use of asbestos began in the manufacturing of cremation cloths, lamp wicks, hats and shoes. Later on, asbestos application became widespread in all kinds of living… Read article →