NGS Pre-Analytics


targeted DNA sequencing

Targeted DNA sequencing: why you might miss some mutations

One of our favorite things here at QIAGEN is the concept of targeted DNA sequencing. If you haven’t heard about it yet, it’s an approach that involves enriching specific regions of a gene prior to NGS. More scientists have been adopting this strategy recently because it has three key advantages over whole-genome sequencing. Namely, targeted… Read article →


next-generation sequencing

From sample to insight: NGS for liquid biopsy and beyond

The use of high-throughput next-generation sequencing (NGS) technologies continues to provide a wealth of sequence data, resulting in significant advances in a wide range of research areas and applications. Key among these is liquid biopsy – the ability to sequence nucleic acids found in circulation will enable scientists to identify key mutations and more specifically distinguish… Read article →



Sequencing_Bacteria_700x233

If you can’t grow it, you can’t study it. How can we sequence unculturable bacteria?

Sequencing bacteria helps us detect mutations that might be important for antibiotic resistance, virulence changes and other variations within a species. A major complication, though, is the fact that not every bacterium can be successfully grown in culture. So how can you sequence something when you can’t culture it? A recent study points to the… Read article →