PCR Solutions

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Webinar takeaways – “Accurate DNA Methylation Analysis by Successful Bisulfite Conversion”

DNA methylation is widely recognized as a major player regulating normal gene expression and facilitating chromatin organization within cells. Research into abnormal DNA methylation that leads to human diseases like cancer could therefore provide valuable insights for disease development diagnosis and potential therapies. DNA is made up of 4 nucleotides – cytosine, guanine, thymine and… Read article →


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Back to the future – 30 years of plasmid purification

What would happen if we traveled 30 years back in a QIAGEN time machine? In 1986, it all started with the first QIAGEN kit for plasmid purification, giving scientists all over the world a revolutionary alternative to anion-exchange and phenol chloroform extraction. But back then, would we have believed that plasmid purification kits would become… Read article →


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Emerging roles of competing endogenous RNA (ceRNA)

If you have been following our blog posts about microRNA (miRNA) – or if you have been studying the microRNA world – you are likely familiar with the small 22-nucleotide RNAs that target messenger RNAs (mRNAs) to repress their translation into protein. The ceRNA hypothesis In 2011, Pier Paolo Pandolfi research lab proposed the hypothesis… Read article →


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Cannabis epigenetic control of skin differentiation genes

Did you know that there is a “Hash, Marihuana & Hemp Museum” located in Amsterdam, Netherlands? Dedicated to education and scientific studies, this world-famous museum has received more than 2 million visitors since 1985. Despite its controversial uses and long banning histories, cannabis (commonly referred to as marijuana) and its chemical derivatives have been found… Read article →