The quality of extracted genomic DNA (gDNA) is a critical factor in many downstream applications, such as real-time PCR or multiplex PCR. Successful extraction of gDNA from formalin-fixed and paraffin-embedded (FFPE) tissues remains a challenge. Therefore, it’s good to get back to the basics of sample purification, multiplex PCR and quality control in order to… Read article →
Love, life, health and vitality. All are connected through one symbol: the beating of a heart. Often we don’t notice the strength of this organ until it starts to beat fast enough in our chests that we can feel it. One of the most beautiful instances of a racing heart happens during social bonding and when we fall in… Read article →
A cascade of complex genetic and epigenetic changes regulate tumor formation and progression. Gene expression analyses can shed light on these changes at a molecular level and identify the key genes and associated pathways involved in cancer. Often the samples used in cancer research are FFPE samples, which pose a significant challenge in terms of nucleic acid… Read article →
Strategies to counter tumor heterogeneity are high on the wish list of oncologists and cancer researchers. Within a single tumor, cells can differ in size, proliferation rate and ability to metastasize. Most significantly for physicians and patients, they can also differ in their sensitivity to chemotherapy. How can we best understand and investigate this aspect… Read article →
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease, has received a high level of attention due to the ALS Ice Bucket Challenge that went viral across the internet a few years back. You probably had a friend who accepted the Ice Bucket Challenge on social media, or perhaps did the challenge yourself. But… Read article →
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