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Webinars on-demand: Digital NGS for RNA-seq, miRNA-seq and DNA-seq!

Digital NGS using Unique Molecular Indices (UMIs) is a game-changer in RNA-seq, miRNA-seq and DNA-seq, enabling accurate quantification by overcoming PCR bias. In May, we presented the details of this technology for gene expression, microRNA analysis and mutation detection as part of our NGS Week webinar series, and again in July as part of the Summer of… Read article →




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Four questions you should ask about your library prep

Comparing new enzymatic methods with physical shearing One of the key components to a successful sequencing run is library prep – and the first step in any great library is DNA fragmentation. Fragmentation cuts DNA into sizes that sequencers such as Illumina or Ion Torrent instruments can handle. Considering all the options out there to… Read article →


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Effective genomic DNA removal – crucial for accurate gene expression analysis

Whether you are working with formalin-fixed, paraffin embedded (FFPE) tissue or normal tissue samples, the elimination of genomic DNA (gDNA) from your RNA preps is crucial to obtain reliable results in gene expression analysis, especially if you want to determine the gene expression pattern in a specific cell or under specific conditions. Possible consequences of… Read article →