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Maintaining biospecimen integrity during transfers

Biospecimens are usually kept in storage for the majority of their “lifetimes,” but the brief moments when they are being transferred are the moments they are most at risk. Regardless of whether the purpose for transfer is consolidation, storage reorganization or replacing damaged containers, maintaining the appropriate temperature for the type of samples and their… Read article →



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Keeping an eye on microRNA in retinal degeneration

The field of microRNA research is in a period of inflection. While RNAi and microRNA have been growing in prominence since discoveries by Dr. Craig Melo and Dr. Andy Fire looking at the relationship of small, non-coding RNA with gene expression, there has been a growing sense of the importance of detecting and correlating microRNA… Read article →


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microRNAs in cancer metastasis: potential for therapy and liquid biopsy

For patients with solid tumors, metastatic disease often represents a turning point in their journey. It remains the most significant hurdle in cancer treatment, accounting for 90% of all deaths resulting from solid tumors (1). Research during the past 20 years has begun to elucidate multiple events that take place during metastatic progression. In the… Read article →


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Critical factors for successful molecular analysis of FFPE samples

Formalin fixation and paraffin embedding (FFPE) can impair the quality of nucleic acids obtained from tissue samples. The molecular analysis of FFPE samples is negatively affected by the low quality of analytes from FFPE samples. Taking this into consideration is important when performing successful molecular analyses. In this post, we’ll discuss how FFPE affects RNA… Read article →