targeted DNA sequencing

Targeted DNA sequencing: why you might miss some mutations

One of our favorite things here at QIAGEN is the concept of targeted DNA sequencing. If you haven’t heard about it yet, it’s an approach that involves enriching specific regions of a gene prior to NGS. More scientists have been adopting this strategy recently because it has three key advantages over whole-genome sequencing. Namely, targeted… Read article →



CancerPathwayFinder_700x233

ncRNAs as circulating cancer biomarkers for liquid biopsy

Cancer biomarkers are critical at multiple points during the disease process. Novel biomarkers for cancer screening, obtained via liquid biopsies, would be of particular clinical value given the difficulty of early detection for lethal malignancies such as ovarian and pancreatic cancer. Even cancers that are easily detected could benefit from improved screening and staging methods…. Read article →


microRNA and lncRNA in lung cancer

miRNA and lncRNA – serum biomarkers for lung cancer

One of the most exciting potential applications of circulating non-coding RNAs like microRNA (miRNA) and long non-coding RNA (lncRNA) is as biomarkers for early detection of cancer. Cancer treatment, like treatment of many other diseases, can be far more effective when started early. Easily accessible markers like RNAs in the blood are an attractive possibility for finding… Read article →