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Advances in sequencing single cells – a PCR-free method for NGS RNA library construction

In our last post, “How can you construct NGS DNA libraries from a single cell in just one day?”, we discussed how to prepare a DNA NGS library from a single cell. What are the differences when preparing libraries for RNA-seq? We know that a number of conventional whole transcriptome amplification methods already overcome limited RNA availability,… Read article →




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Brainy exosomes: a novel pool for biomarker discovery in human CSF

Exosomes, endocytic vesicles ranging in size from 40–100nm, have revolutionized the field of cell–cell communication. Although they were first described in the 1980s, detailed analysis of exosome biogenesis, composition and function has occurred primarily within the past decade. The significance of exosomes is enhanced by the fact that exosomes transport packets of cellular information rather… Read article →


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Maintaining biospecimen integrity during transfers

Biospecimens are usually kept in storage for the majority of their “lifetimes,” but the brief moments when they are being transferred are the moments they are most at risk. Regardless of whether the purpose for transfer is consolidation, storage reorganization or replacing damaged containers, maintaining the appropriate temperature for the type of samples and their… Read article →