As Christmas is approaching, it’s time to wrap up warm, listen to Christmas songs and wait for Santa to arrive on his sleigh. Rudolph the Red Nosed Reindeer is one of those well-known Christmas characters, however, his unique red nose and how he is able to fly still remain a mystery. Rudolph´s real-life counterpart, also… Read article →
Cell-free circulating tumor DNA (ctDNA) is fragmented DNA from tumors (160–180 base pairs) that is found in the cell-free part of whole blood (i.e., plasma and serum) (1, 2). ctDNA can be distinguished from normal cell-free DNA (cfDNA) by the presence of somatic mutations (2). Analysis of ctDNA has the potential to be a ‘liquid… Read article →
The 6th Annual International Society of Extracellular Vesicles (ISEV) 2017 conference earlier this spring in Toronto, CA, offered exosome and extracellular vesicle (EV) researchers new information and exciting ideas to explore. Standouts for this year’s meeting included an introduction to EV-TRACK, a new interactive database for standardizing EV protocols and an introductory plenary talk by… Read article →
About 20–30% of breast cancer tumors overexpress the oncogene human epidermal growth factor receptor 2 (HER2), which – if not treated with a targeted anti-HER2 regimen – leads to higher aggressiveness and mortality. Recently, a number of studies have shown that expression of HER2 in circulating tumor cells (CTCs) varies compared to expression in primary tumors…. Read article →
It can be a real struggle sometimes to find and select the right isolation kit, whether it is for RNA or genomic DNA (gDNA) purification. Not using the right kit for your experiments has major consequences, however – the impact could be as severe as not being able to publish your results. Or worse, finding that other researchers were able… Read article →
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