Posts Tagged: blood

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New webinar: HER2, CTCs and tumor stemness

About 20–30% of breast cancer tumors overexpress the oncogene human epidermal growth factor receptor 2 (HER2), which – if not treated with a targeted anti-HER2 regimen – leads to higher aggressiveness and mortality. Recently, a number of studies have shown that expression of HER2 in circulating tumor cells (CTCs) varies compared to expression in primary tumors…. Read article →


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One spin, one dedicated kit – selection wheels make it possible

It can be a real struggle sometimes to find and select the right isolation kit, whether it is for RNA or genomic DNA (gDNA) purification. Not using the right kit for your experiments has major consequences, however – the impact could be as severe as not being able to publish your results. Or worse, finding that other researchers were able… Read article →



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Biofluid microRNA profiling

The development of biomarkers will be essential for the future of diagnostic, prognostic and predictive medicine. Diagnostic biomarkers may be used to detect cancer, heart failure, stroke or a number of other diseases. Prognostic biomarkers predict patient outcome, while predictive biomarkers are essential for determining whether a cancer patient will respond to targeted therapy. Unfortunately, the translation… Read article →


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Multiple sclerosis: hunting for new RNA markers in blood

Multiple sclerosis (MS), a rare and chronic central nervous system disorder resulting from autoimmunity, occasionally steps into the public eye when it strikes a well-known person (such as in 1999, when talk show host Montel Williams revealed his diagnosis). In neuroscience and immunology laboratories, however, the disease is always a major topic of investigation. Researchers… Read article →