Cancer stem cells (CSCs) represent an extremely small subpopulation of tumor cells and are characterized by the ability to self-renew and differentiate. This special group of tumor cells has a slower growth rate relative to other tumor cells, endowing CSCs with high resistance to traditional chemo and radiation therapies that target rapidly dividing cells (1)…. Read article →
Lung cancer is the most common cancer worldwide, with non-small-cell lung carcinoma (NSCLC) accounting for more than 1 in 10 of all cancers diagnosed in men (1). More than 30 years ago, epidermal growth factor receptor (EGFR) was identified as being more concentrated in human lung tumors than in normal lung membrane tissue (2). EGFR… Read article →
Reactive oxygen species (ROS) are chemical molecules containing a highly reactive oxygen molecule. These molecules are formed as by-products of cellular metabolism, but also serve intracellularly as signaling molecules. ROS examples include peroxides, superoxide, hydroxyl radical and singlet oxygen. When present within cells in significant amounts, ROS can be indicators of oxidative cellular stress, and… Read article →
The song “A day in the life” sung by The Beatles has always been one of my favorites and probably the reason why many people contemplate what they do in their daily lives. Although I moved from academia to industry several years ago, I still have good friends working as post-doctorates who are specifically involved… Read article →
To say tumor biology is complex is an understatement. Not only can tumors vary genetically, phenotypically and metabolically, there are even differences in cells within a single tumor. Collectively, this is referred to as tumor heterogeneity, and is used as a basis for the classification of tumors into subtypes, predominantly based on cancer-specific genomic or… Read article →
07/27/2017
In this webinar, we discuss how new technological advances have helped overcome the challenges of miRNA-seq and RNA-seq, and why NGS is replacing qPCR as the technology of choice for total RNA discovery studies.
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07/26/2017
Join us and learn how you can easily upgrade your RNA-seq data and move beyond the limits of qPCR, microarray and traditional RNA-seq using targeted RNA sequencing.
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Mark your calendars, applications are due August 14 for the #Microbiome Awards! Details: https://t.co/cBLsa8f0PH https://t.co/mskNQ73N8n, Join us for the summer of NGS! Find out more: https://t.co/UlQRlzcbvb https://t.co/ucwu3i5ncj, Single-cell NGS webinar: Find out how to apply NGS to your single-cell research! https://t.co/D8Qn6gaU58 https://t.co/Ujjayn8Y4m, New PBMC study on practical know-how for total RNA isolation - download the study https://t.co/97tMVJtOmc https://t.co/rt6c4mCwYB, 
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