Posts Tagged: cancer

S_4652_GG_visual

Webinar download: Automate and standardize processes for cell-free DNA in liquid biopsy

Circulating, cell-free DNA (cfDNA), which can originate from malignant tumors, the developing fetus or inflammatory tissues, is present among the cell-free nucleic acids in plasma, serum and other body fluids. Recently, cfDNA has become a powerful tool in non-invasive prenatal testing (NIPT), as well as in liquid biopsy for cancer. Analysis of cfDNA allows for… Read article →


ILLU_0633_MCF_IncRNAs_s

Big things in small packages for liquid biopsy: extracellular communication via exosomes

Cells utilize multiple mechanisms to send messages. Long-range signaling, the production of molecules from a single organ which then travel through the bloodstream to the rest of the body, is regulated by the endocrine system. Signaling molecules secreted by the endocrine system include steroid hormones, growth factors, glycoproteins and catecholamines. The list of endocrine organs… Read article →



serum+plasma_miRNA_700x233

microRNAs in cancer metastasis: potential for therapy and liquid biopsy

For patients with solid tumors, metastatic disease often represents a turning point in their journey. It remains the most significant hurdle in cancer treatment, accounting for 90% of all deaths resulting from solid tumors (1). Research during the past 20 years has begun to elucidate multiple events that take place during metastatic progression. In the… Read article →


LungCancer+miRNA_700x233

Cancer in the lungs? The blood will tell – miRNA in non-small cell lung cancer

In a previous post, we discussed how small non-coding RNAs could be identified to serve as circulating biomarkers in lung cancer. Now, a new study from Ma et al. defines a promising microRNA signature in peripheral blood mononuclear cells. The signature can distinguish non-small cell lung carcinoma (NSCLC) with 72.62% sensitivity and 82.61% specificity, and squamous… Read article →