Posts Tagged: cancer

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Emerging roles of competing endogenous RNA (ceRNA)

If you have been following our blog posts about microRNA (miRNA) – or if you have been studying the microRNA world – you are likely familiar with the small 22-nucleotide RNAs that target messenger RNAs (mRNAs) to repress their translation into protein. The ceRNA hypothesis In 2011, Pier Paolo Pandolfi research lab proposed the hypothesis… Read article →


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Top 10 FAQs on circulating tumor cells

During the past 20 years, the interest in circulating tumor cells (CTCs) has increased dramatically due to their potential as circulating biomarkers in monitoring cancer progression and treatment. However, selecting and detecting CTCs from whole blood of cancer patients in the background of normal cells is very challenging. Since last summer, Dr. Siegfried Hauch, Director… Read article →


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Towards personalized cancer care: liquid biopsy for monitoring primary breast cancer

Breast cancer is the most common cancer in women, accounting for 23% of all cancer diagnoses (1). At the time of diagnosis, a majority of patients (>90%) will have localized disease, which is typically treated with surgery, radiation and therapeutic agents. Localized disease is associated with improved five-year survival rates, relative to more advanced cancers… Read article →


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Newly discovered biomarker miR-591 inhibits cancer cell proliferation and invasion

About 5000 years ago, the inhabitants in east Finland first discovered asbestos and used it to make their cooking utensils strong (1). In the mid-19th Century, the large-scale industrial use of asbestos began in the manufacturing of cremation cloths, lamp wicks, hats and shoes. Later on, asbestos application became widespread in all kinds of living… Read article →