Posts Tagged: cancer

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Circulating tumor cell (CTC) biomarkers in liquid biopsy – not ready for prime time?

Currently, the only FDA-approved use of circulating tumor cells (CTCs) is identifying and counting CTCs in whole blood from patients with metastatic breast, colon or prostate cancer (1). Based upon recent developments, enumeration of CTCs is only the tip of the iceberg. Molecular characterization of CTCs would permit noninvasive genotyping in real time, potentially sampling… Read article →


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Day 3 at ASHG 2015: Real-life application of genetic variations

(Editor’s note: Missed the earlier ASHG recaps? Find them here! Day One Day Two) In yesterday’s blog, I talked about genetic variability and some concerns about its usefulness. So today, I attended a late evening session, “Clinical Impact of Genetic Variation,” to learn more about how these findings are being used for clinical purposes. The session was led by… Read article →


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October Webinar Feature: Single cell analysis

Do you wonder what you might find if you narrowed your genomic and transcriptomic analyses down to the single-cell level? If you suppressed the noise from ten thousand other cells, what might an individual cell have to say? Single-cell analysis is a burgeoning area of interest, spurred by advances in sequencing technology. Down to the… Read article →



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Webinar download: Automate and standardize processes for cell-free DNA in liquid biopsy

Circulating, cell-free DNA (cfDNA), which can originate from malignant tumors, the developing fetus or inflammatory tissues, is present among the cell-free nucleic acids in plasma, serum and other body fluids. Recently, cfDNA has become a powerful tool in non-invasive prenatal testing (NIPT), as well as in liquid biopsy for cancer. Analysis of cfDNA allows for… Read article →