Posts Tagged: FFPE

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A 3-part webinar series: Overcoming challenges in gDNA-based research, multiplex PCR and quality control

The quality of extracted genomic DNA (gDNA) is a critical factor in many downstream applications, such as real-time PCR or multiplex PCR. Successful extraction of gDNA from formalin-fixed and paraffin-embedded (FFPE) tissues remains a challenge. Therefore, it’s good to get back to the basics of sample purification, multiplex PCR and quality control in order to… Read article →



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Still using xylene to manually extract DNA from your FFPE samples?

For decades, formalin-fixed paraffin-embedded (FFPE) tissue samples have been collected and archived for long-term storage. They’re extremely valuable for carrying out research like mutation screening or pathogen detection. In general, deparaffinization of the FFPE tissue sections is achieved by manual xylene pretreatment, which dissolves the paraffin from the tissue, and a series of ethanol washes… Read article →


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One spin, one dedicated kit – selection wheels make it possible

It can be a real struggle sometimes to find and select the right isolation kit, whether it is for RNA or genomic DNA (gDNA) purification. Not using the right kit for your experiments has major consequences, however – the impact could be as severe as not being able to publish your results. Or worse, finding that other researchers were able… Read article →