Posts Tagged: microRNA

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Join our 2-part webinar series! Intro to qPCR and role of RNAs as biomarkers in cardiovascular research

Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality worldwide. Preventative and therapeutic strategies focused on controlling traditional risk factors have not always been successful. Recently, the use of miRNAs as novel biomarkers in CVD has opened up new possibilities for discovering novel therapeutic targets and understanding CVD development. To date, the total… Read article →


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Webinar highlights – Maximizing miRNA-seq success from liquid biopsy samples

Development of markers that facilitate earlier and non-invasive diagnosis is a primary goal of disease research. This is where microRNAs come in. Studies have indicated that the expression levels of these non-coding RNA molecules are altered in disease states, including cancer and neurodegeneration. Evidence of their presence in biofluids means that their potential as important… Read article →




Biogenesis

Eliminating contaminants in miRNA-seq libaries just got easier

microRNA sequencing is not only useful for finding novel microRNAs and detecting isomiRs; it’s also an attractive method for miRNA expression profiling, particularly when combined with molecular indexing to boost quantification accuracy (see our previous post, Barcodes in NGS: sample vs molecular). But preparing a library to sequence purely microRNAs can be difficult due to contaminating… Read article →