Posts Tagged: microRNA

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microRNAs in cancer metastasis: potential for therapy and liquid biopsy

For patients with solid tumors, metastatic disease often represents a turning point in their journey. It remains the most significant hurdle in cancer treatment, accounting for 90% of all deaths resulting from solid tumors (1). Research during the past 20 years has begun to elucidate multiple events that take place during metastatic progression. In the… Read article →


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Cancer in the lungs? The blood will tell – miRNA in non-small cell lung cancer

In a previous post, we discussed how small non-coding RNAs could be identified to serve as circulating biomarkers in lung cancer. Now, a new study from Ma et al. defines a promising microRNA signature in peripheral blood mononuclear cells. The signature can distinguish non-small cell lung carcinoma (NSCLC) with 72.62% sensitivity and 82.61% specificity, and squamous… Read article →


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New webinar shows synergy between two miRNA detection techniques

In our last post, we discussed the strengths and weaknesses of the three most popular techniques for miRNA detection, qPCR, miRNA-seq and microarray. We ultimately concluded that these miRNA detection technologies are appropriate for different experimental circumstances, and a lab’s decision about which to use should be driven by their research goals. Today, I’m excited to report on a presentation about… Read article →



microRNA and lncRNA in lung cancer

miRNA and lncRNA – serum biomarkers for lung cancer

One of the most exciting potential applications of circulating non-coding RNAs like microRNA (miRNA) and long non-coding RNA (lncRNA) is as biomarkers for early detection of cancer. Cancer treatment, like treatment of many other diseases, can be far more effective when started early. Easily accessible markers like RNAs in the blood are an attractive possibility for finding… Read article →