Posts Tagged: miRNA


ILLU_0920_OvarianCancer_Metastasis

Discovering microRNA biomarkers in cancer

In recent years, research into microRNA biomarkers for cancer has expanded, yielding many potential signatures for a variety of cancer types. MicroRNAs are promising biomarker candidates due to their stability in circulation in association with Ago2, HDL or extracellular vesicles, and their important gene regulation roles in multiple cancer-related processes. Multiple methods are available for miRNA… Read article →


Exosomes digestive tract

MicroRNA sorting in exosomes and determination of cell fate

Liquid biopsy, that is, sampling and analysis of DNA, RNA and proteins found in blood or other body fluids, offers a potentially non-invasive and cost-effective way to gain insight into cancer and other disease detection and progression. Within blood, both healthy and diseased cells release small vesicles termed extracellular vesicles (EVs) that carry information from… Read article →



Biogenesis

miRNA-seq vs qPCR in 2017: an update

Time marches on and technology with it, and these new advances yield new perspectives. Of particular interest to this blog is the changing technology and perspective on microRNA profiling methods. Two years ago, I wrote about the pros and cons of 3 methods commonly used for miRNA expression analysis, NGS, qPCR and microarray, and concluded… Read article →