Posts Tagged: miRNA

Biogenesis

miRNA-seq – when should you use it, and what are the challenges?

Exploring microRNA expression and function has led to some important discoveries about the regulation of gene expression in normal biological processes and disease states, and has even recently given rise to unique circulating biomarker signatures. qPCR and microarrays are the traditional techniques used to assess microRNA expression, and they have their strong points – qPCR… Read article →


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What is the future of microRNA technology?

Technology for profiling of microRNA by qPCR is ever evolving, opening up the opportunity for deeper insights into gene regulation. The development of locked nucleic acids (LNA), for example, enhanced qPCR primer specificity, while the design for an effective reverse transcription method for plant microRNAs opened up a new phylogenetic kingdom for qPCR profiling. Developing assays to… Read article →


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One spin, one dedicated kit – selection wheels make it possible

It can be a real struggle sometimes to find and select the right isolation kit, whether it is for RNA or genomic DNA (gDNA) purification. Not using the right kit for your experiments has major consequences, however – the impact could be as severe as not being able to publish your results. Or worse, finding that other researchers were able… Read article →


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The Bioscientist Webinar Festival – a pool of educational content

Here at QIAGEN, one of our main aims is to provide you with excellent, actionable resources that will support you in your research and experiments. As a result, we create content on a regular basis that can help you gain insights into important topics of scientific and specialized interest. As part of this ongoing effort,… Read article →


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Newly discovered biomarker miR-591 inhibits cancer cell proliferation and invasion

About 5000 years ago, the inhabitants in east Finland first discovered asbestos and used it to make their cooking utensils strong (1). In the mid-19th Century, the large-scale industrial use of asbestos began in the manufacturing of cremation cloths, lamp wicks, hats and shoes. Later on, asbestos application became widespread in all kinds of living… Read article →