Posts Tagged: NGS


miRNAs+Barcodes_V01

Webinar highlights – Maximizing miRNA-seq success from liquid biopsy samples

Development of markers that facilitate earlier and non-invasive diagnosis is a primary goal of disease research. This is where microRNAs come in. Studies have indicated that the expression levels of these non-coding RNA molecules are altered in disease states, including cancer and neurodegeneration. Evidence of their presence in biofluids means that their potential as important… Read article →




Biogenesis

Eliminating contaminants in miRNA-seq libaries just got easier

microRNA sequencing is not only useful for finding novel microRNAs and detecting isomiRs; it’s also an attractive method for miRNA expression profiling, particularly when combined with molecular indexing to boost quantification accuracy (see our previous post, Barcodes in NGS: sample vs molecular). But preparing a library to sequence purely microRNAs can be difficult due to contaminating… Read article →