Posts Tagged: PCR

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Where to tread carefully – how to ensure reliability in microRNA biomarker studies

Accuracy, reliable controls and reproducibility. These are the foundations on which a healthy scientific literature is based. When we read papers, we check the methods section to see how the authors controlled for certain variables, whether the technologies used were appropriate for the question, and how many times the experiments were replicated. Everyone wants to find the… Read article →


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Critical factors for successful molecular analysis of FFPE samples

Formalin fixation and paraffin embedding (FFPE) can impair the quality of nucleic acids obtained from tissue samples. The molecular analysis of FFPE samples is negatively affected by the low quality of analytes from FFPE samples. Taking this into consideration is important when performing successful molecular analyses. In this post, we’ll discuss how FFPE affects RNA… Read article →