Posts Tagged: PCR

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March webinar series: Explore the host response and defense mechanisms

The immune system is an intricate host defense system of unique, yet highly coordinated responses to pathogens. The immune response is divided into two phases – innate and adaptive. Innate immunity provides the first line of defense through different families of pattern-recognition receptors (PRRs), such as Toll-like receptors (TLRs). Adaptive immunity, in the form of… Read article →



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Where to tread carefully – how to ensure reliability in microRNA biomarker studies

Accuracy, reliable controls and reproducibility. These are the foundations on which a healthy scientific literature is based. When we read papers, we check the methods section to see how the authors controlled for certain variables, whether the technologies used were appropriate for the question, and how many times the experiments were replicated. Everyone wants to find the… Read article →


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Critical factors for successful molecular analysis of FFPE samples

Formalin fixation and paraffin embedding (FFPE) can impair the quality of nucleic acids obtained from tissue samples. The molecular analysis of FFPE samples is negatively affected by the low quality of analytes from FFPE samples. Taking this into consideration is important when performing successful molecular analyses. In this post, we’ll discuss how FFPE affects RNA… Read article →