Posts Tagged: qPCR

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The PD1 race picks up pace

If you’ve been following developments in cancer immunotherapy closely, you’ve probably heard of programmed death 1 (PD1/PDCD1, also known as CD279) and PDL1 (CD274). Their interaction is at the center of new immune checkpoint-targeting therapies coming out of the pharmaceutical industry, such as Bristol-Myers Squibb’s nivolumab and Merck’s pembrolizumab (1, 5). What are PD1 and PDL1, and… Read article →



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Emerging roles of competing endogenous RNA (ceRNA)

If you have been following our blog posts about microRNA (miRNA) – or if you have been studying the microRNA world – you are likely familiar with the small 22-nucleotide RNAs that target messenger RNAs (mRNAs) to repress their translation into protein. The ceRNA hypothesis In 2011, Pier Paolo Pandolfi research lab proposed the hypothesis… Read article →


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Cannabis epigenetic control of skin differentiation genes

Did you know that there is a “Hash, Marihuana & Hemp Museum” located in Amsterdam, Netherlands? Dedicated to education and scientific studies, this world-famous museum has received more than 2 million visitors since 1985. Despite its controversial uses and long banning histories, cannabis (commonly referred to as marijuana) and its chemical derivatives have been found… Read article →