Posts Tagged: samples


Phenol-based and non-phenol-based methods for extracting exosomal RNA

Studies in recent years have established that RNA contents in exosomes can serve as biomarkers for certain cancers (1). As exosomal RNA becomes more critical to research, successful isolation of these nanovesicles has become equally fundamental. Exosomes are small (40–100 nm) nanovesicles containing RNA that can move between cells. Found in several biological fluids, including blood plasma… Read article →


Starting on the right foot – how to optimize RNA sample quality

RNA is one of the most important samples in molecular biology. In your lab’s personal biobank, you might extract RNA from any number of sample types, from frozen cells to FFPE tissue, and the insights you can gain from analyzing it are crucial. Messenger RNA links genes to proteins, and transcriptome profiling can reveal much about the workings… Read article →


Biorepositories: implications of international collaborations

Research studies require high-quality samples in sufficient number to produce statistically significant results.  Although biobanks have been collecting samples for decades, recent trends have emphasized large-scale projects, extensive clinical information associated with samples, and an emphasis on whole-genome analysis techniques (1). Biobanks are now significant players in clinical research studies, and international compatibility is a… Read article →