Posts Tagged: samples

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Starting on the right foot – how to optimize RNA sample quality

RNA is one of the most important samples in molecular biology. In your lab’s personal biobank, you might extract RNA from any number of sample types, from frozen cells to FFPE tissue, and the insights you can gain from analyzing it are crucial. Messenger RNA links genes to proteins, and transcriptome profiling can reveal much about the workings… Read article →



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Biorepositories: implications of international collaborations

Research studies require high-quality samples in sufficient number to produce statistically significant results.  Although biobanks have been collecting samples for decades, recent trends have emphasized large-scale projects, extensive clinical information associated with samples, and an emphasis on whole-genome analysis techniques (1). Biobanks are now significant players in clinical research studies, and international compatibility is a… Read article →



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Biobanking: the impact of low-concentration storage on RNA integrity

Biobanks frequently freeze samples to store them for future research use, but maintaining quality of nucleic acids under frozen conditions can be tricky. Following specific quality practices can ensure the preservation of RNA, which is crucial for maintaining samples for clinical studies. Storage conditions, including the temperature and the length of time tissues and purified RNA stay… Read article →