Posts Tagged: samples


Biorepositories: implications of international collaborations

Research studies require high-quality samples in sufficient number to produce statistically significant results.  Although biobanks have been collecting samples for decades, recent trends have emphasized large-scale projects, extensive clinical information associated with samples, and an emphasis on whole-genome analysis techniques (1). Biobanks are now significant players in clinical research studies, and international compatibility is a… Read article →


Biobanking: the impact of low-concentration storage on RNA integrity

Biobanks frequently freeze samples to store them for future research use, but maintaining quality of nucleic acids under frozen conditions can be tricky. Following specific quality practices can ensure the preservation of RNA, which is crucial for maintaining samples for clinical studies. Storage conditions, including the temperature and the length of time tissues and purified RNA stay… Read article →


Understanding what factors contribute to variations in quantity of DNA purified from FFPE materials

QIAGEN recently presented a webinar exploring what factors contribute to variations in quantity of DNA purified from FFPE material. As noted in “Top 5 considerations for preparing and archiving FFPE samples,” FFPE is a standard method for long-term preservation of DNA in tissue biopsies. It’s critical to understand how to overcome the challenges that this sample type presents in order… Read article →