Posts Tagged: samples

Biobank_Freezers_700x233

Cryopreservation as a method for long-term sample storage

Cryopreservation (cryogenic preservation) is “the storage of cells, tissues and organs following appropriate ‘preparatory’ procedures at the ultra-low temperature of liquid nitrogen (–196°C).” (1) This form of preservation is ideal for biobanking because these cold temperatures slow chemical and physical reactions of the biomolecules and biospecimens and stop the samples from degrading. Liquid nitrogen biobanks… Read article →


S_4600_GEN_Co42-66699776_s

The 12 SOPs every biobank should have

High-quality biobanked samples closely resemble the biospecimen prior to extraction, with minimal modification due to collection or storage conditions. Establishment of standard operating procedures (SOPs) is crucial to avoid introducing variables into your research samples during storage and maintain the high quality required for reliable results. According to current recommendations, there are 12 SOPs that… Read article →



S_4599_GEN_GI525440859_s

Maintaining biospecimen integrity during transfers

Biospecimens are usually kept in storage for the majority of their “lifetimes,” but the brief moments when they are being transferred are the moments they are most at risk. Regardless of whether the purpose for transfer is consolidation, storage reorganization or replacing damaged containers, maintaining the appropriate temperature for the type of samples and their… Read article →


S_1992_FFPE_0686_16zu9

Critical factors for successful molecular analysis of FFPE samples

Formalin fixation and paraffin embedding (FFPE) can impair the quality of nucleic acids obtained from tissue samples. The molecular analysis of FFPE samples is negatively affected by the low quality of analytes from FFPE samples. Taking this into consideration is important when performing successful molecular analyses. In this post, we’ll discuss how FFPE affects RNA… Read article →